Kathleen Aren

The paper identifies immune cell populations and gene expression differences associated with non-inflammatory pain in RA patients using flow cytometry and single-cell RNA-seq.

The paper identifies profibrotic monocyte-derived alveolar macrophages as a biomarker and therapeutic target in SSc-ILD by analyzing BAL fluid and lung explants.

The paper uses RNA-Seq to analyze SSc patient and control samples, identifying SPAG17 and SOX9 non-coding RNAs as novel factors in SSc pathogenesis.

This study identifies three monocyte transcriptional subgroups in SSc patients that correlate with disease activity, particularly lung function.

This paper uses machine learning to classify heart disease subgroups in systemic sclerosis using echocardiographic and skin transcriptome data, identifying distinct phenotypes and associated molecular pathways.