Evan Spruijt

This study investigates how amyloidogenic proteins like synuclein adsorb to biomolecular condensates and how this process can be modulated to slow aggregation.

The paper investigates how amino acids interact with phase-separating proteins to modulate biomolecular condensate stability and dynamics.

The paper quantifies ion binding to biomolecular condensates using NMR and shows that ion uptake follows water affinity matching, affecting condensate microenvironment and biochemical processes.

This study identifies PMLII as forming biomolecular condensates at sites of nuclear envelope disruption, suggesting a role in stabilizing the site for repair.

This study investigates how varying ratios of HspB2 and HspB3 affect their phase behavior, revealing reversible condensates and aggregates with distinct molecular compositions.