Pierre Verrelle

This study uses single-cell RNA sequencing to show that radiotherapy induces pro-angiogenic signaling in human lung tissue, including upregulation of VEGFA and changes in capillary and macrophage populations.

The paper investigates the role of DNA methylation and H3K27me3 in transcriptional alterations in glioma, finding that H3K27me3 defects are more prevalent than DNA methylation defects in gene deregulation.