Yan Li

This study identifies microRNA-146a as an endogenous activator of TLR7 signaling, which promotes embryonic HSC development through IRF5 and Notch signaling in zebrafish and mouse embryos.

This study shows that Lacticaseibacillus rhamnosus P118 enhances host resistance to Salmonella by promoting indole metabolites from gut microbes.

This study examines the evolution of the resistome in Salmonella Gallinarum during its transition to endemicity, revealing localized mobilome-driven resistance profiles.

The paper shows that MyD88-dependent TLR signaling in endothelial cells reduces hematopoietic stem cells (HSCs) while increasing committed progenitors and intra-arterial hematopoietic cluster cells by promoting their proliferation.

The paper identifies a pre-hematopoietic (pre-HE) stage in mouse embryos and shows RUNX1 regulates the transition to hemogenic endothelium, leading to distinct HSPC populations in intra-arterial clusters.