Molecular BiologyJournal of Molecular Cell BiologyPeer-reviewed
Observation of an α-synuclein liquid droplet state and its maturation into Lewy body-like assemblies
Maarten C. Hardenberg, Tessa Sinnige, Sam Casford…·Michele Vendruscolo
The paper shows that α-synuclein forms liquid droplets that mature into amyloid-rich hydrogels, suggesting Lewy body formation is linked to arrested maturation in the presence of lipids.
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