Author
University of GroningenORCID 0000-0003-4841-6358Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
Recent·Most cited
Christopher Brasnett, Chelsea M. Brown, Linus Grünewald, Jan A. Stevens, Siewert J. Marrink
This paper parameterizes 186 common metabolites for the Martini 3 force field to enable realistic simulations of metabolite interactions in biological systems.
Journal of Chemical Theory and Computation · May 26, 2026Peer-reviewedBiophysics
José Losa, François Simon, Dmitrii Linnik, S. Kaya, Marc C. A. Stuart, Artem Stetsenko, Rinse de Boer, Franz Y. Ho, Danny Incarnato, Jan A. Stevens, Jan van Eck, Marco W. Fraaije, Lucien E. Weiss, Sven van Teeffelen, Sanne Abeln, , Matthias Heinemann
The paper shows that protein agglomerates in E. coli regulate cytoplasmic rheology, with diffusion inversely correlating with amino acid metabolism protein abundance.
Molecular Cell · Apr 10, 2026Peer-reviewedBiophysics
Fabian Schuhmann, Jan A. Stevens, Neda Rahmani, Isabell Lindahl, Chelsea M. Brown, Christopher Brasnett, Dimitrios Anastasiou, Adrià Bravo Vidal, Beatrice J. Geiger, Siewert J. Marrink, Weria Pezeshkian
The paper introduces TS2CG version 2, a tool for building coarse-grained membrane structures with specific shapes and lateral organization, demonstrating its capabilities through various simulations.
Journal of Chemical Theory and Computation · Sep 2, 2025Peer-reviewedBiophysics
Chelsea M. Brown, M. S. S. Westendorp, Rubí Zarmiento-García, Jan A. Stevens, Bart M. H. Bruininks, Sarah L. Rouse, Siewert J. Marrink, Tsjerk A. Wassenaar
The paper presents a workflow to create a comprehensive model of a mitochondrial crista junction using a coarse-grained representation and molecular modelling.
Communications Biology · Jul 1, 2025Peer-reviewedBiochemistry
Nishita Mandal, Jan A. Stevens, Adolfo B. Poma, Bartłomiej Surpeta, Carlos Eduardo Sequeiros-Borja, Aravind Selvaram Thirunavukarasu, Siewert J. Marrink, Jan Brezovský
This study benchmarks coarse-grained simulation methods for analyzing enzyme transport tunnels, finding they efficiently capture tunnel geometry but vary in replicating all-atom dynamics.
bioRxiv · Sep 16, 2024 · PreprintBioinformatics