Weria Pezeshkian

The paper shows that APP-CTFβ regulates glutamatergic synaptic transmission and that Aβ counteracts its hyperexcitability effects in Alzheimer's disease.

This paper develops a 3D-printed microfluidic chip with synchrotron SAXS for real-time monitoring of hexosome formation and identifies key parameters affecting their structure.

This paper introduces a method to measure spontaneous curvature in cellular membranes using tether pulling and simulations, revealing baseline negative curvature and its modulation by treatments.

This study shows that membrane fluctuations can drive protein clustering and organization without direct interactions, using mesoscale simulations to demonstrate the role of membrane rigidification and curvature.

A hybrid 4D whole-cell simulation of the minimal bacterium JCVI-syn3A integrates spatial reaction-diffusion, metabolism, polymer chromosome dynamics, and division across a complete 105-minute cell cycle.

This study investigates how membrane neck size responds to pressure gradients, revealing a two-phase behavior with implications for nuclear envelope mechanics and synthetic membrane design.

The paper introduces TS2CG version 2, a tool for building coarse-grained membrane structures with specific shapes and lateral organization, demonstrating its capabilities through various simulations.

The paper introduces HMFF, a method integrating experimental data into membrane simulations, and applies it to various biological systems to enable multi-scale modeling.

The paper uses integrative molecular dynamics simulations to analyze cross-linking mass spectrometry data and reveal mitochondrial protein distributions, including the localization of FAM162A and TMEM126A in cristae.

This study uses molecular dynamics simulations to show that membrane curvature affects lipid sorting and phase behavior in complex ways beyond traditional models.

This paper introduces a DNA-based tool called SMS to generate controlled liposome shapes like stomatocytes and dumbbells, compatible with protein reconstitution.