Author

Muhammad Jasrie Firdaus

Nanyang Technological UniversityORCID 0000-0003-4843-9605Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:metabolomics· 1 Assay:proteomics· 1

Frequent Co-Authors

Franklin L. ZhongiD· 2 shared John CommoniD· 2 shared Rae ChuaiD· 2 shared Shirley Suet Lee Ding· 2 shared Stephen WearneiD· 2 shared Bin Wu· 1 shared Chai Yoke Tin· 1 shared Étienne MeunieriD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersImmunology

Franklin L. ZhongORCID

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintJan 25, 2026

Two orthogonal MAP3K-driven pathways of NLRP1 inflammasome activation revealed by poisonous beetles.

Rae Chua, Stephen Wearne, Shirley Suet Lee Ding…·Franklin L. Zhong

This paper identifies two distinct MAP3K pathways activated by beetle toxins that trigger NLRP1 inflammasome activation in human keratinocytes.

1 citation

humanproteomics

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ImmunologybioRxivPreprintAug 13, 2025

Clarifying the priming requirement and activator specificity for the NLRP3 inflammasome in human keratinocytes in vitro

Pritisha Rozario, Ying Shiang Lim, Shirley Suet Lee Ding…·Franklin L. Zhong

This study investigates NLRP3 inflammasome activation in human keratinocytes, showing it is induced by IFN-gamma but not LPS, and that specific activators like Hla target NLRP3 while nigericin activates both NLRP1 and NLRP3.

3 citations

humanexperimental assay

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