David O. Bates

This paper shows that inhibiting SRPK1 in monocytes promotes angiogenesis by altering VEGF splicing from anti-angiogenic VEGF-A165b to pro-angiogenic VEGF-A165a in both human and mouse models of peripheral arterial disease.

This study shows that AT1 receptor activation in dorsal horn pericytes causes vasoconstriction and pain hypersensitivity, which can be prevented by losartan.

The paper uses intravital imaging in mice to study spinal cord vascular permeability and function in real time.

The paper shows that hypoxia in the spinal dorsal horn, caused by vascular issues, activates sensory neurons and leads to neuropathic pain, which can be reversed by inhibiting carbonic anhydrase.