Author

Nicolas Werschler

University of British ColumbiaORCID 0000-0003-4860-8587Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Daniel Aguilar‐HidalgoiD· 2 shared Joel ÖstblomiD· 2 shared M. Mona SiuiD· 2 shared Mukul TewaryiD· 2 shared Peter W. ZandstraiD· 2 shared Andrew HagneriD· 1 shared Benjamin McMasteriD· 1 shared Himanshu KauliD· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersDevelopmental Biology

Daniel Aguilar‐HidalgoORCID

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2 papers

Recent·Most cited

Developmental BiologybioRxivPreprintDec 20, 2022

Symmetry-breaking in adherent pluripotent stem cell-derived developmental patterns

Daniel Aguilar‐Hidalgo, Joel Östblom, M. Mona Siu…·Peter W. Zandstra

The paper uses a computational model and experiments to show that small micro-patterned mPSC colonies exhibit spontaneous asymmetry in BRA-GFP patterns, suggesting a mechanism for symmetry-breaking in development.

2 citations

mousebulk RNA-seq

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Developmental BiologyStem Cell ReportsPeer-reviewedNov 3, 2022

Gene regulatory network (GRN) embedded agents connect cellular decision making to human pluripotent stem cell derived germ layer-like pattern formation

Himanshu Kaul, Nicolas Werschler, Ross D. Jones…·Peter W. Zandstra

The paper develops a GRN model embedded in cellular agents to simulate hPSC lineage commitment and shows how GRN wiring influences germ layer pattern formation.

21 citations

humanbulk RNA-seq

𝕏 PostBluesky