Author

Sabateeshan Mathavarajah

Dalhousie UniversityORCID 0000-0003-4871-1373Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

Elias B. HabibiD· 2 shared Graham DellaireiD· 2 shared Jayme SalsmaniD· 2 shared Adam David DurbiniD· 1 shared Alexander LaVeck· 1 shared Andrew J. RogeriD· 1 shared Andrew Lee HongiD· 1 shared Annika L. GustafsoniD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersCell Biology

Elias B. HabibORCID

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3 papers

Recent·Most cited

Cancer BiologybioRxivPreprintSep 3, 2026

Synergistic targeting of EP300/CBP and EYA co-activators collapses the rhabdomyosarcoma core regulatory circuit

Annika L. Gustafson, Stephanie Nance, Berkley E. Gryder…·Adam David Durbin

The paper identifies a core regulatory circuit in rhabdomyosarcoma and shows that targeting two co-activators synergistically inhibits tumor growth.

DOI 10.64898/2026.09.02.748955

humanbulk RNA-seq

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Cell BiologyCell ReportsPeer-reviewedJun 16, 2025

The evolutionarily conserved PRP4K-CHMP4B/vps32 splicing circuit regulates autophagy

Sabateeshan Mathavarajah, Sandhya Chipurupalli, Elias B. Habib…·Graham Dellaire

This study identifies a conserved PRP4K-CHMP4B/vps32 splicing circuit that regulates autophagy in both human cells and Dictyostelium discoideum.

DOI 10.1016/j.celrep.2025.115870

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Molecular BiologyNucleic Acids ResearchPeer-reviewedFeb 24, 2023

PML and PML-like exonucleases restrict retrotransposons in jawed vertebrates

Sabateeshan Mathavarajah, Kathleen L. Vergunst, Elias B. Habib…·Graham Dellaire

This study identifies PML and PML-like exonucleases as cytoplasmic suppressors of LINE-1 retrotransposition in jawed vertebrates, showing functional conservation across species.

16 citations

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