ImmunologyDevelopmentPeer-reviewed
Depletion and replacement of tissue resident macrophages in mice with germ-line deletion of a conserved enhancer in the Csf1r locus.
Yajun Liu, Sébastien Jacquelin, Isis Taylor…·David Arthur Hume
This study shows that mice with a germ-line deletion of a Csf1r enhancer lack specific macrophages but maintain normal physiology and can be replenished by donor cells.
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