Author
University of WashingtonORCID 0000-0003-4874-5557Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
William L. White, Hua Bai, Chun Kim…·David A. Baker
This paper designs soluble, miniaturized MHC proteins that enable stable expression in E. coli and retain peptide and TCR binding specificity.
Stephen Rettie, David Juergens, Victor Adebomi…·Gaurav Bhardwaj
This paper introduces RFpeptides, a deep learning framework for designing high-affinity macrocyclic peptides, achieving sub-nanomolar binding affinities and accurate structural predictions.
Danny D. Sahtoe, Ewa A. Andrzejewska, Hannah L. Han…·David A. Baker
The paper designs peptide traps that bind amyloidogenic segments in {beta}-strand and {beta}-hairpin conformations, effectively blocking fibril assembly for A{beta}42.