ImmunologybioRxivPreprint
Type I and III interferons synergize with TNF to promote virally-triggered damage to the intestinal epithelium
Lucie Bernard, Jessica Anne Neil, Kayla Kim…·Ken Cadwell
The paper shows that IFN-β and IFN-λ, along with TNF, promote epithelial cell death in mice and human organoids, especially in those with ATG16L1 mutations, linking it to intestinal disease.