Jessica Anne Neil

This study compares viral replication and host responses in airway epithelial cells to distinguish pathogenic from seasonal coronaviruses, finding HCoV-229E induces severe epithelial injury despite limited replication.

The paper shows that IFN-β and IFN-λ, along with TNF, promote epithelial cell death in mice and human organoids, especially in those with ATG16L1 mutations, linking it to intestinal disease.

This study isolates and characterizes contemporary seasonal human coronaviruses, showing differences in cell tropism and growth compared to lab-adapted strains.

This study compares traditional mAb infusion with mRNA/LNP-based de novo mAb expression in mice, finding high serum concentrations but compromised protective capacity due to anti-drug antibodies.