Author
University College LondonORCID 0000-0003-4925-6798Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Dongwei Xu, Youngah Kim, Sharifah Anoar…·Teresa Niccoli
This paper shows metformin protects neurons by stabilizing rngo/DDI2, enhancing proteostasis and reducing toxicity in multiple neurodegenerative models.
Dunxin Shen, Alec J. Vincent, Evan Udine…·Teresa Niccoli
The paper identifies neuronal vulnerability to C9orf72 repeat expansion by analyzing transcriptional states in a Drosophila model, finding that Xbp1 expression correlates with resistance to toxicity.
Ashling Giblin, Alexander J. Cammack, Niek Blomberg…·Adrian M. Isaacs
The paper identifies reduced PUFA levels in FTD/ALS models and shows neuronal PUFA supplementation improves survival and reduces neuronal death.
Dongwei Xu, Alec J. Vincent, Andrés González‐Gutiérrez…·Teresa Niccoli
This study shows that increasing pyruvate import in neurons rescues dementia-like phenotypes in fly models by clearing toxic protein deposits.