Author

Andrés González‐Gutiérrez

University of ChileORCID 0000-0002-9441-2211Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:Drosophila· 3 Approach:experimental assay· 3 Assay:electrophysiology· 1 Research Focus:synaptic & neural circuits· 1

Frequent Co-Authors

Jimena A. SierraltaiD· 3 shared Adrian M. IsaacsiD· 1 shared Alec J. VincentiD· 1 shared Andrés Esparza· 1 shared Andrés Ibacache· 1 shared Andres KōhleriD· 1 shared Annora ThoengiD· 1 shared Ashling GibliniD· 1 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersNeuroscience

Jimena A. SierraltaORCID

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3 papers

Recent·Most cited

Presynaptic PMCA interacts with Dlg, regulating in vivo synaptic calcium in Drosophila larval NMJ

Andres Kōhler, Estefania Lopez, Eduardo Quiroz, Oliver Kobler, Andres Enrique Gonzalez-Gutierrrez, Ulrich Thomas, Jimena A Sierralta

This study shows that PMCA interacts with Dlg to regulate presynaptic calcium levels in Drosophila NMJ, affecting neurotransmitter release and Ca2+ homeostasis.

bioRxiv · Nov 4, 2026 · PreprintNeuroscience

A monocarboxylate transporter rescues frontotemporal dementia and Alzheimer's disease models

Dongwei Xu, Alec J. Vincent, Andrés González‐Gutiérrez, Benjamin Aleyakpo, Sharifah Anoar, Ashling Giblin, Magda Luciana Atilano, Mirjam Lisette Adams, Dunxin Shen, Annora Thoeng, Elli Tsintzas, Marie Emilie Maeland, Adrian M. Isaacs, Jimena A. Sierralta, Teresa Niccoli

This study shows that increasing pyruvate import in neurons rescues dementia-like phenotypes in fly models by clearing toxic protein deposits.

PLoS Genetics · Sep 21, 2023Peer-reviewedNeuroscience

Monocarboxylate Transport In Drosophila Larval Brain During Low And High Neuronal Activity

Andrés González‐Gutiérrez, Andrés Ibacache, Andrés Esparza, L. Felipe Barros, Jimena A. Sierralta

This study characterizes monocarboxylate transport in Drosophila larval brain under different activity levels, showing glial cells are more efficient in lactate/pyruvate transport and maintain a lactate gradient towards neurons.

bioRxiv · Apr 15, 2019 · PreprintNeuroscience