Christopher Dostal

This study identifies FAHD1 as a critical regulator of mitochondrial function and cardiomyocyte maturation, showing its deficiency impairs respiration, disrupts sarcomere organization, and leads to cardiac dysfunction.

This study uses single-cell transcriptomics to compare GLP1R expression in human and mouse cardiac tissues and organoids, finding cardiac expression is low in mice but increased in human heart disease.

This study shows CD8+ T cells drive energy substrate redistribution between lymphoid organs and the heart during viral infection, with metabolic adaptations affecting cardiac function.

This study shows empagliflozin enhances peak sodium current in Nav1.5 channels by acting as a pharmacological chaperone, potentially reducing arrhythmia risk in Duchenne muscular dystrophy.