Cécile Philippe

Stress-induced Metabolic Remodeling of Adipose and Brain Tissue Revealed by Positron Emission Tomography

This study uses PET and multi-OMICS to show stress activates brown adipose tissue and alters brain metabolism in mice, identifying metabolic hubs and signatures relevant to mental health and disease models.

Injury size regulates glucose allocation locally and systemically during vertebrate tissue regeneration

This study shows that injury size affects glucose allocation during tail regeneration in axolotls, with larger injuries leading to increased local and systemic glucose uptake.

Thyroid Hormone Receptor Beta Signaling is a Targetable Driver of Prostate Cancer Growth

This study identifies TRβ as a driver of prostate cancer growth and shows that NH-3 inhibits PCa cell proliferation and tumor growth, particularly in castration-resistant models.

CD8+ T cells regulate the bioenergetic reprogramming of lymphoid organs and the heart during viral infection

This study shows CD8+ T cells drive energy substrate redistribution between lymphoid organs and the heart during viral infection, with metabolic adaptations affecting cardiac function.