Christina S. Ennis

This study investigates how metabolic dysfunction and metformin affect plasma extracellular vesicle signaling to prostate cancer cells, identifying specific miRNAs and their effects on tumor progression.

This study investigates how AMPK and BET proteins regulate immune checkpoint molecules in TNBC patients with T2D, suggesting personalized ICB treatment strategies.

This study creates a large integrated single-cell RNA-seq atlas of human breast cancers, revealing tumor microenvironment heterogeneity and survival-associated cell states across multiple datasets.

The paper shows that inhibiting the CoREST complex with corin alters RNA splicing, increases neoantigen expression, and enhances tumor immunity in melanoma.

This study shows that exosomes from type 2 diabetes patients promote breast cancer aggressiveness in organoids by expanding immunosuppressive cells and increasing tumor heterogeneity and invasiveness.