Author

Yu Sun

Humboldt-Universität zu BerlinORCID 0009-0000-1041-6593Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Yu Sun15 papers · Cornell University

Biology Disciplines

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Molecular Biology· 2 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Assay:long-read sequencing· 2 Organism:yeast· 2 Approach:benchmark study· 1 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Assay:proteomics· 1

Frequent Co-Authors

Ann E. Ehrenhofer‐MurrayiD· 3 shared Bhargesh Indravadan Patel· 2 shared Franziskus HauthiD· 2 shared Christoph DieterichiD· 1 shared Julia BäriD· 1 shared Lisa Mallis· 1 shared Marin BoutonnetiD· 1 shared Marina MikhaylovaiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersMolecular Biology

Ann E. Ehrenhofer‐MurrayORCID

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3 papers

Recent·Most cited

NeurosciencebioRxivPreprintJul 8, 2026

The gut microbiota-derived metabolite queuosine regulates neuronal development and network function through tRNA modification

Ning Yang, Yu Sun, Lisa Mallis…·Marina Mikhaylova

This study shows that queuosine (Q) modification of tRNA enhances neuronal development and synaptic activity in cultured rat cortical neurons.

DOI 10.64898/2026.07.02.736043

𝕏 PostBluesky

Molecular BiologyBMC GenomicsPeer-reviewedJun 29, 2026

Evaluation of Dorado v5.2.0 de novo basecalling models for the detection of tRNA modifications using RNA004 chemistry

Bhargesh Indravadan Patel, Franziskus Hauth, Yu Sun, Ann E. Ehrenhofer‐Murray

This study evaluates Dorado v5.2.0 basecalling models for detecting tRNA modifications using RNA004 chemistry, finding improved pseudouridine detection but challenges in complex modification environments.

2 citations

yeastlong-read sequencing

𝕏 PostBluesky

Molecular BiologyNucleic Acids ResearchPeer-reviewedAug 1, 2025

MoDorado: Enhanced detection of tRNA modifications in nanopore sequencing by off-label use of modification callers

Franziskus Hauth, Wang Liu-Wei, Yu Sun…·Ann E. Ehrenhofer‐Murray

The paper introduces MoDorado, an algorithm that detects tRNA modifications beyond those trained in existing models, identifying seven new modifications in S. pombe.

18 citationstop 3%

yeastlong-read sequencing

𝕏 PostBluesky