Author

J. C. M. Chan

Oklahoma Medical Research FoundationORCID 0009-0000-2285-2042Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Charmain F. JohnsoniD· 1 shared Courtney T. GriffiniD· 1 shared George E. DavisiD· 1 shared Jun XieiD· 1 shared Kate Wheeler· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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5 top collaborators · 10 mutual co-author links

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1 shared paperPathology

Charmain F. JohnsonORCID

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1 paper

Recent·Most cited

PathologybioRxivPreprintDec 31, 2025

TNFα and Endothelial IL-1 Receptor Signaling Drive Peritubular Capillary Regression and Fibrosis in Obstructive Kidney Injury

Charmain F. Johnson, Kate Wheeler, Jun Xie…·Courtney T. Griffin

This study identifies TNF and endothelial IL-1R1 signaling as key drivers of capillary regression and fibrosis in obstructive kidney injury, showing that their combined inhibition preserves peritubular capillaries and reduces renal injury.

1 citation

mouseexperimental assay

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