Charmain F. Johnson

This study identifies TNF and endothelial IL-1R1 signaling as key drivers of capillary regression and fibrosis in obstructive kidney injury, showing that their combined inhibition preserves peritubular capillaries and reduces renal injury.

This study shows that endothelial RIPK3 reduces vascular permeability and inflammation in ischemia-reperfusion injury by regulating IL-6 secretion and adhesion molecule expression.