Author

Mira Loock

McGill UniversityORCID 0009-0000-4738-6463Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:proteomics· 2 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Assay:long-read sequencing· 1 Research Focus:variant calling· 1 Assay:whole-genome sequencing· 1 Organism:yeast· 1

Frequent Co-Authors

Igor dos Santos CestariiD· 3 shared Lissa Cruz‐SaavedraiD· 2 shared Luiza Berenguer AntunesiD· 2 shared Andressa Brito LiraiD· 1 shared Antonio Alfonso De Lauri· 1 shared Rhiannon HeslopiD· 1 shared Valeria Bernal AraujoiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 14 mutual co-author links

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3 shared papersMicrobiology

Igor dos Santos CestariORCID

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3 papers

Recent·Most cited

MicrobiologybioRxivPreprintJun 13, 2026

A genome wide antigen-antibody screen identifies a yeast-based therapeutic vaccine candidate for Chagas disease

Mira Loock, Lissa Cruz‐Saavedra, Valeria Bernal Araujo, Igor dos Santos Cestari

The paper identifies a yeast-based therapeutic vaccine candidate for chronic Chagas disease by screening T. cruzi antigens with patient antibodies and validating its efficacy in mice.

DOI 10.64898/2026.06.12.731947

proteomicsexperimental assay

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MicrobiologybioRxivPreprintApr 7, 2025

Stochastic variation in surface protein expression diversifies Trypanosoma cruzi infection

Lissa Cruz‐Saavedra, Mira Loock, Luiza Berenguer Antunes, Igor dos Santos Cestari

This study shows stochastic variation in virulence gene expression in T. cruzi helps diversify infection and evade immune recognition.

1 citation

proteomicslong-read sequencing

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Molecular BiologyMethods and ProtocolsPeer-reviewedSep 21, 2023

High-efficiency transformation and expression of genomic libraries in yeast

Mira Loock, Luiza Berenguer Antunes, Rhiannon Heslop…·Igor dos Santos Cestari

This paper presents an optimized electroporation protocol for high-efficiency yeast transformation, enabling efficient expression of whole-genome libraries with minimal DNA input.

23 citations

yeastwhole-genome sequencing

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