ImmunologybioRxivPreprint
TCR signal strength during positive selection shapes CD25 expression patterns on thymically derived regulatory T cells
Isabel Baldwin, Dunfang Zhang, Yash Kulkarni…·Ellen A. Robey
DOI 10.64898/2026.06.16.732736
Author
University of California, BerkeleyORCID 0009-0000-4797-7052Unclaimed ORCID profile · follow to get notified of new preprints
2 papers
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Isabel Baldwin, Dunfang Zhang, Yash Kulkarni…·Ellen A. Robey
Zoë Steier, Dominik A. Aylard, Laura Lynn McIntyre…·Aaron Streets
This study uses CITE-seq to analyze thymocyte development and identifies TCR signaling waves and the TCR/calcineurin/NFAT/GATA3 axis as drivers of CD4/CD8 lineage commitment.