Author
University of California, BerkeleyORCID 0000-0003-4436-3826Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Esther Jeong Yoon Kim, Dominik A. Aylard, Zoë Steier…·Ellen A. Robey
The paper shows preselection CD4+CD8+ thymocytes undergo gene expression changes linked to reduced TCR responsiveness and impaired CD4 fate gene upregulation, connecting these changes to T cell lineage commitment.
Hanlin Zhang, C. Kimberly Tsui, Jesse Garcia Castillo…·Andrew G. Dillin
This study shows that aging reduces 2,6-linked sialic acids on T cells, leading to exhaustion and impaired immune function.
Esther Jeong Yoon Kim, Lydia M. Sorokin, Takashi Hiiragi
The paper shows that ECM-integrin adhesion enables cells to sense their position and specify ICM fate in early mouse embryos.
Zoë Steier, Dominik A. Aylard, Laura Lynn McIntyre…·Aaron Streets
This study uses CITE-seq to analyze thymocyte development and identifies TCR signaling waves and the TCR/calcineurin/NFAT/GATA3 axis as drivers of CD4/CD8 lineage commitment.