Robby Concha-Eloko

This paper models phage depolymerase capsular tropism using graph neural networks and sequence clustering, showing predictive ability and transferability to lytic phages.

The paper isolates and characterizes phages targeting Klebsiella pneumoniae clinical isolates, showing that specific phage hunting is more effective than broad-spectrum approaches for infection control.

DepoScope uses large language models to accurately annotate phage depolymerases and their domains, improving detection through sequence and amino-acid level predictions.