Hailey Sounart

ProbeST designs custom probe sets for spatial transcriptomics, validated on mouse enteroids infected with Salmonella, enabling detection of host and pathogen transcripts.

This paper presents a method to simultaneously detect host and SARS-CoV-2 transcriptomes in lung tissue and identifies pathway shifts in infected cells.

The paper demonstrates miniature spatial transcriptomics to study gene expression patterns in filarial worms and their Wolbachia endosymbionts, revealing spatial gene localization and interactions.