Nina Hobi

A single-donor iPSC-derived alveolar chip with epithelial, endothelial and macrophage cells models early Mycobacterium tuberculosis infection and shows ATG14-deficient macrophages die more without extra bacterial replication.

This paper develops a Lung-on-Chip model to study SARS-CoV-2 infection in the alveolar barrier and demonstrates its utility for drug testing.

The paper demonstrates biocontrol using oxalotrophic bacteria to combat Aspergillus niger in a mouse infection model by interfering with oxalic acid production.