Author

Alessandra S. Miller

Mayo ClinicORCID 0009-0000-5939-9296Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 1 Pharmacology & Toxicology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Assay:electronic health records· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Colin ReardoniD· 2 shared Eric Jung· 2 shared Gatha Pore· 2 shared Jane LiiD· 2 shared Jungjae ParkiD· 2 shared Maithili BanginwariD· 2 shared Mélanie G. GareauiD· 2 shared Sarah LeeiD· 2 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersPhysiology

Colin ReardonORCID

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3 papers

Recent·Most cited

PhysiologyProceedings of the National Academy of SciencesPeer-reviewedSep 23, 2026

Neonatal Enteric Infection Disrupts the Microbiota-Gut-Brain Axis Through Pattern Recognition Receptors and Altered Neuroimmune Signaling

Jungjae Park, Olivia Orahood, Maithili Banginwar…·Mélanie G. Gareau

This study shows that neonatal EPEC infection disrupts the microbiota-gut-brain axis via NOD1 signaling, leading to long-term neuroimmune and behavioral deficits, and identifies probiotic muropeptides as potential therapeutics.

2 citations

mouseproteomics

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Pharmacology & ToxicologyEnvironmental PollutionPeer-reviewedAug 6, 2026

Oral exposure to Perfluorooctanoic acid disrupts the microbiota-gut-liver axis and enhances the severity of chemically induced colitis in mice.

Jungjae Park, Alessandra S. Miller, Gatha Pore…·Mélanie G. Gareau

This study shows that early-life PFOA exposure disrupts the gut-liver axis and worsens DSS-induced colitis in male mice but not in genetically predisposed Il10 KO mice.

2 citations

mousebulk RNA-seq

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NeurosciencebioRxivPreprintJun 30, 2024

Rod-shaped microglia interact with neuronal dendrites to regulate cortical excitability in TDP-43 related neurodegeneration

Manling Xie, Alessandra S. Miller, Praveen N. Pallegar…·Long‐Jun Wu

The paper identifies rod-shaped microglia in a TDP-43 mouse model that interact with neuronal dendrites to reduce cortical hyperexcitability and protect against neurodegeneration.

8 citations

mousespatial transcriptomics

𝕏 PostBluesky