Molecular BiologybioRxivPreprint
Non-canonical activation of IRE1a during Candida albicans infection enhances macrophage fungicidal activity
Michael J. McFadden, Mack B. Reynolds, Britton C Michmerhuizen…·Teresa R. O’Meara
This study shows that Candida albicans activates IRE1 in macrophages through non-canonical mechanisms, enhancing fungicidal activity by promoting phagolysosomal fusion.
DOI 10.1101/2023.10.02.560560