Author
University of MichiganORCID 0000-0001-6014-4637Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Zachary M. Powers, Michael J. McFadden, Gi Young Lee…·Mary X O’Riordan
This study shows that Salmonella Typhi uses asparaginase to deplete asparagine, activating the GCN2 kinase and the integrated stress response in murine macrophages, which enhances bacterial killing.
Mikel D. Haggadone, Brian P. Goldspiel, Aoife O’Farrell…·Will Bailis
This study shows that environmental branched-chain amino acids regulate ASC translation and NLRP3 inflammasome assembly through mTOR-dependent translational bursting.
Michael J. McFadden, Mack B. Reynolds, Britton C Michmerhuizen…·Teresa R. O’Meara
This study shows that Candida albicans activates IRE1 in macrophages through non-canonical mechanisms, enhancing fungicidal activity by promoting phagolysosomal fusion.