Author

Baylee A. Smith

University of PittsburghORCID 0009-0000-6565-5567Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:chromatin & epigenetic regulation· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1 Assay:proteomics· 1

Frequent Co-Authors

Isabella Walter· 2 shared Matthew L. WohleveriD· 2 shared Chan Hyun NaiD· 1 shared Daein Kim· 1 shared Deepika GauriD· 1 shared Dominic T. CastanzoiD· 1 shared Doohyung Lee· 1 shared Kyle M. MilleriD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersBiochemistry

Isabella Walter

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3 papers

Recent·Most cited

BiochemistryProtein Expression and PurificationPeer-reviewedApr 28, 2025

Overcoming Fluorescence Loss in mEOS-based AAA+ Unfoldase Reporters Through Covalent Linkage

Isabella Walter, Baylee A. Smith, Dominic T. Castanzo, Matthew L. Wohlever

The paper develops a method to use mEOS-based reporters for membrane-associated AAA+ unfoldases by covalently linking mEOS to a degron via Sortase, preserving fluorescence and enabling functional analysis.

DOI 10.1016/j.pep.2025.106724

protein structureexperimental assay

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BiochemistrybioRxivPreprintSep 23, 2024

Energetic requirements and mechanistic plasticity in Msp1-mediated substrate extraction from lipid bilayers

Baylee A. Smith, Deepika Gaur, Nathan D. Walker…·Matthew L. Wohlever

This study investigates how Msp1 uses ATP hydrolysis to extract transmembrane helices from lipid bilayers, finding a non-linear relationship between ATP hydrolysis and extraction efficiency.

2 citations

experimental assay

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Cell BiologyMolecular CellPeer-reviewedJan 1, 2024

TRIM24 directs replicative stress responses to maintain ALT telomeres via chromatin signaling

Daein Kim, Ragini Bhargava, Shih-Chun Wang…·Kyle M. Miller

This study identifies TRIM24's role in ALT telomere maintenance through chromatin signaling, showing it promotes telomere DNA synthesis via SUMO-dependent mechanisms.

12 citations

humanproteomics

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