Adeline Goulet

This study reports cryo-EM structures of phage OE33PA, revealing a dynamic adhesion device that mediates Gram-positive host recognition through receptor-binding proteins and a hexameric tape measure protein.

The paper determines the cryo-EM structure of Jabs, a bacteriophage infecting Mycobacterium abscessus, revealing unique capsid assembly and adhesion features.

This study characterizes Tle1, a bactericidal toxin from Pseudomonas aeruginosa, and identifies its interactions with VgrG4a, Tla1, and Tli1a, revealing the molecular mechanisms of its delivery and inhibition.

This paper engineers CRISPR-Cas9 variants from Streptococcus thermophilus to target diverse A-rich PAMs, enabling efficient genome editing in mice.