NeurosciencebioRxivPreprint
Dysregulated functional and metabolic response in multiple sclerosis patient macrophages correlate with a more inflammatory state, reminiscent of trained immunity
Jennifer Fransson, Corinne Bachelin, Florence Deknuydt…·Violetta Zujovic
The paper examines MS patient macrophages and finds they exhibit a pro-inflammatory transcriptomic and metabolic profile, suggesting intrinsic immune cell memory and potential therapeutic targets.
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