Élisabeth Maillart

Functional Immuno-metagenomics Seizes the Alteration of Microbiota-Immune Interactions at the Early Onset of Multiple Sclerosis

The paper develops IMscore and IMGindex to assess gut microbiota-immune interactions and identify aberrant microbe-immune responses in early Multiple Sclerosis.

Genetic architecture of Multiple Sclerosis patients in the French national OFSEP-HD cohort

The paper analyzes the genetic architecture of MS patients in the OFSEP-HD cohort, identifies ancestral clusters, and presents a synthetic dataset for data sharing.

Dysregulated functional and metabolic response in multiple sclerosis patient macrophages correlate with a more inflammatory state, reminiscent of trained immunity

The paper examines MS patient macrophages and finds they exhibit a pro-inflammatory transcriptomic and metabolic profile, suggesting intrinsic immune cell memory and potential therapeutic targets.