Patient-derived lymphocytes drive smoldering lesion pathology in a chimeric multiple sclerosis mouse model
Océane Perrot, Mathias Nordbeck, Corinne Bachelin…·Violetta Zujovic
This study shows that MS patient-derived lymphocytes in a chimeric mouse model drive smoldering lesion pathology, impair functional recovery, and alter CNS cell populations and myelination.