Chloe Jenniches

The paper develops a CRISPR/Cas9-based method for efficient fluorescent protein knock-in in sea urchins by using a split-fluorescent protein strategy, achieving higher integration efficiency than conventional methods.

This study creates a single-cell atlas of gene expression, transcription, and chromatin accessibility in sea urchin embryos, revealing dynamic regulatory elements and lineage-specific gene activation patterns.

This study develops an automated high-throughput HCR pipeline to rapidly map expression of 101 genes in sea urchin embryos, enabling large-scale discovery of novel developmental gene expression patterns.