Svenja Kling

The paper develops a CRISPR/Cas9-based method for efficient fluorescent protein knock-in in sea urchins by using a split-fluorescent protein strategy, achieving higher integration efficiency than conventional methods.

This study develops an automated high-throughput HCR pipeline to rapidly map expression of 101 genes in sea urchin embryos, enabling large-scale discovery of novel developmental gene expression patterns.

This paper establishes the first germline transgenic sea urchin using the Minos transposon, enabling stable transgene integration and inheritance.

The paper identifies 18 cell types in sponges, including neuroid cells with synaptic gene expression, suggesting early neuro-immune system evolution.

This study identifies HAS-7, an astacin proteinase, as a Wnt processing factor that regulates head formation in Hydra by controlling Wnt ligand activity and axis patterning.