S. cerevisiae Cwc15p Tunes the Spliceosome Active Site for Remodeling and Catalysis
Natalie J Zeps, Giovanni Balice, Elizabeth Baudhuin…·Aaron A. Hoskins
This study investigates the role of Cwc15p in S. cerevisiae splicing, finding it stabilizes and facilitates structural transitions of the spliceosome active site, important for splicing under nonoptimal conditions.