Author

Tucker J. Carrocci

University of Wisconsin–MadisonORCID 0000-0002-6272-0885Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 2 Genetics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:yeast· 2 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Aaron A. HoskinsiD· 3 shared Ali G. GharaviiD· 1 shared Alina Christine HilgeriD· 1 shared Andreas KispertiD· 1 shared Cade T. Harkner· 1 shared Caroline Maria KolvenbachiD· 1 shared Csenge K. ReziiD· 1 shared Esben LorentzeniD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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3 shared papersBiochemistry

Aaron A. HoskinsORCID

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3 papers

Recent·Most cited

BiochemistryACS Chemical BiologyPeer-reviewedJan 12, 2026

A Yeast-Based High-Throughput Screening Platform for the Discovery of Novel pre-mRNA Splicing Modulators

Sierra L. Love, Henrik Vollmer, Ya‐Chu Chang…·Aaron A. Hoskins

This paper develops a yeast-based high-throughput screening platform to identify small molecules modulating pre-mRNA splicing, identifying 4 compounds and showing one affects splicing in cancer cells with a splicing factor mutation.

DOI 10.1021/acschembio.5c00867

yeastproteomics

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GeneticsbioRxivPreprintJul 16, 2025

CAKUT variants in PRPF8, DYRK2, and CEP78: implications for splicing and ciliogenesis

Lea Maria Merz, Shirlee Shril, Tucker J. Carrocci…·Friedhelm Hildebrandt

The paper identifies variants in PRPF8 and related genes associated with CAKUT, showing their role in splicing and ciliogenesis through functional experiments.

1 citation

humanmouse

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BiochemistrybioRxivFeb 4, 2024

Functional Analysis of the Zinc Finger Modules of the S. cerevisiae Splicing Factor Luc7

Tucker J. Carrocci, Samuel DeMario, Kevin He…·Aaron A. Hoskins

This study investigates the role of zinc finger domains in the yeast splicing factor Luc7 using humanized variants, revealing their impact on splice site selection and interactions with Prp28.

DOI 10.1261/rna.079956.124

yeastexperimental assay

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