Ciaran J. McCoy

This study shows that flagellum assembly and BBSome integrity are essential for Leishmania mexicana pathogenicity, while flagellar motility is not required for infection.

The paper identifies essential membrane transporters for Leishmania survival through a CRISPR-Cas9 gene deletion screen, finding that V-ATPase is critical for amastigote survival despite being dispensable for promastigote growth.

This study identifies 2143 flp-genes across 100+ nematode species, revealing evolutionary patterns and expression dynamics of FLPs in parasitic nematodes.

This study introduces a novel computational pipeline to discover antimicrobial peptides (AMPs) in helminths, revealing unique AMP-like peptides and highlighting their potential as novel antimicrobials.

This study uses in silico analyses to characterize endocannabinoid signaling across nematodes, revealing conservation patterns and potential drug targets in parasitic species.

The paper identifies conserved neuropeptides and their encoding genes in parasitic nematodes and characterizes their physiological activity on reproductive musculature.

The paper identifies divergent neuropeptide-non-coding RNA regulatory networks in Steinernema species IJs that correlate with behavioural differences.