Author

Berfin Seyran

University of California, Los AngelesORCID 0009-0001-1346-5769Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1 Assay:scRNA-seq· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Feiyang MaiD· 1 shared Juliana Shin· 1 shared Kavit RavaliD· 1 shared Lixin YangiD· 1 shared Łukasz SalwińskiiD· 1 shared Matteo A. PellegriniiD· 1 shared Neema JamshidiiD· 1 shared Raju K. PillaiiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCell Biology

Feiyang MaORCID

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1 paper

Recent·Most cited

Cell BiologyLife Science AlliancePeer-reviewedSep 23, 2024

Dysfunctional β-cell longevity in diabetes relies on high energy conservation and positive epistasis

Kavit Raval, Neema Jamshidi, Berfin Seyran…·Slavica Tudzarova

The paper identifies PFKFB3-expressing dysfunctional β-cells in T2D, showing their survival via positive epistasis and reduced clearance, and demonstrates PFKFB3 inhibition restores glucose tolerance in mice.

9 citations

humanmouse

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