Muqing Ma

The paper identifies sigmaE as a key regulator of colistin heteroresistance in Enterobacter cloacae, showing that multiple regulatory systems are required for this resistance.

This study shows that heteroresistance evolves under treatment interruptions in E. coli, using phenotypic flexibility to maintain resistance with minimal fitness cost.

The paper introduces the DnD assay to detect hidden antibiotic resistance mechanisms with high resolution, demonstrating its ability to quantify viable cells over eight orders of magnitude and classify clinical isolates.

The paper shows that glucose availability increases fosfomycin resistance in Enterobacter cloacae by altering GlpT expression and enhancing fosA gene activity.