Author

Lucas L. Figueiredo

Indiana University IndianapolisORCID 0009-0001-2128-6648Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

Alaina M. ReaganiD· 2 shared Amanda A. Bedwell· 2 shared Gareth R. HowelliD· 2 shared Kierra Eldridge· 2 shared Michael SasneriD· 2 shared Paul R. TerritoiD· 2 shared Rachael Speedy· 2 shared Scott A. PersohniD· 2 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersGenetics

Alaina M. ReaganORCID

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2 papers

Recent·Most cited

GeneticsJournal of Cerebral Blood Flow & MetabolismPeer-reviewedSep 1, 2022

The 677C>T variant in methylenetetrahydrofolate reductase causes morphological and functional cerebrovascular deficits in mice

Alaina M. Reagan, Karen E. Christensen, Leah C. Graham…·Gareth R. Howell

This study creates a mouse model with the MTHFR 677C>T variant and shows it causes cerebrovascular deficits, supporting its use in preclinical research on vascular dementia.

21 citations

mouseexperimental assay

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NeuroscienceFrontiers in Aging NeurosciencePeer-reviewedJun 24, 2022

Plcg2M28L interacts with high fat-high sugar diet to accelerate Alzheimers disease-relevant phenotypes in mice

Adrian L. Oblak, Kevin P. Kotredes, Ravi S. Pandey…·Gareth R. Howell

This study shows that a high fat-high sugar diet interacts with the Plcg2M28L genetic variant to accelerate Alzheimer's disease-like phenotypes in mice.

23 citations

mousebulk RNA-seq

𝕏 PostBluesky