Author

Martina Dettenhöfer

Goethe University FrankfurtORCID 0009-0001-2150-2435Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

Andreas KrämeriD· 1 shared Benedict‐Tilman BergeriD· 1 shared Christian Georg KurziD· 1 shared Christopher LenziD· 1 shared Francesco GrecoiD· 1 shared Jennifer Alisa AmrheiniD· 1 shared Joshua Gerninghaus· 1 shared Krishna SaxenaiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

Andreas KrämerORCID

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1 paper

Recent·Most cited

BiochemistryACS Medicinal Chemistry LettersPeer-reviewedOct 14, 2025

Un-LOK-ing a new approach for conformational selective targeting of STK10 (LOK)

Martina Dettenhöfer, Laura Nadine Tandara, Jennifer Alisa Amrhein…·Thomas Hanke

The paper describes the optimization of a macrocyclic scaffold to develop a selective STK10 inhibitor with nanomolar activity and good kinome selectivity.

3 citations

experimental assaydrug response / drug discovery

𝕏 PostBluesky