Pharmacology & ToxicologyThe Journal of Prevention of Alzheimer s DiseasePeer-reviewed
Synaptic Toxicity of OGA Inhibitors and the Failure of Ceperognastat
Jonathan Meade, Haylee Mesa, Shahriar Alamgir…·Qi Zhang
This study shows that OGA inhibitors impair synaptic plasticity and cause synaptotoxic effects in mouse hippocampal slices, suggesting potential risks for Alzheimer's disease therapies.
8 citationstop 1%