Stacy Lok Sze Yam

This study evaluates two methods for quantifying lung volume reduction in ex vivo models, showing they can reduce animal testing and improve preclinical assessment of lung treatments.

The paper shows that cell loss in RPE cells leads to mechanical changes that impair function, mimicking age-related decline in an in vitro model.

This paper develops a photodegradable hydrogel to model age-related ECM deformation, showing that artificial drusen size affects retinal pigment epithelium morphology without disrupting actin cytoskeleton or polarity.