Justin M. Reimertz

This study generates and characterizes human brain border-associated macrophages (BAMs) using iPSC-derived models, showing a conserved hyper-endocytic phenotype across species.

This study identifies brain border-associated macrophages (BAMs) as rhythmic cells regulated by the circadian clock, showing that their endocytic activity and amyloid-beta uptake are disrupted with age and in a mouse model of Alzheimer's disease.

This study identifies the murine dura mater as a transient niche for early-postnatal B lymphopoiesis, highlighting the role of CXCL12-expressing fibroblasts in supporting B cell development.

The paper introduces MACAW, a workflow for detecting errors in genome-scale metabolic models, showing that error types vary with curation methods and that pathway-level errors are particularly challenging.