Author

Theodore M. Fisher

Boston Children's HospitalORCID 0000-0002-4048-3428Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:cell type annotation· 3 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

Akiko IwasakiiD· 1 shared Alec J. WalkeriD· 1 shared Alicia C. Walker· 1 shared Ananya MavinkurveiD· 1 shared Anushree S. Gupte· 1 shared Beth StevensiD· 1 shared Bristy SabikunnahariD· 1 shared Chandler Wright· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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1 shared paperNeuroscience

Akiko IwasakiORCID

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3 papers

Recent·Most cited

IFNγ and proinflammatory cytokines cooperatively license astrocytes to support antigen-dependent CD4+ T cell restimulation

Theodore M. Fisher, Francesco Limone, Matthew D. Smith, Chandler Wright, Petra Kukanja, Peiwen Lu, Kerry C. Limberg, Nicolette Pirjanian, Jimena Zulueta, Valentina Fossati, Akiko Iwasaki, Peter A. Calabresi, Shane Antony Liddelow

The paper shows that IFNγ and proinflammatory cytokines activate astrocytes to express antigen-presenting machinery, supporting CD4+ T cell restimulation in vitro and in vivo.

Cell Reports · Oct 29, 2026Peer-reviewedNeuroscience

Early-life stromal niches orchestrate B lymphopoiesis at the brain's borders

Alec J. Walker, Theodore M. Fisher, Sydney K. Caldwell, Anushree S. Gupte, Justin M. Reimertz, Bristy Sabikunnahar, Samuel E. Marsh, Yvanka de Soysa, Vahid Gazestani, Alicia C. Walker, Youtong Huang, Ananya Mavinkurve, Helena J. Barr, Toby Black Lanser, Sarah R. Murphy, , Beth Stevens

This study identifies the murine dura mater as a transient niche for early-postnatal B lymphopoiesis, highlighting the role of CXCL12-expressing fibroblasts in supporting B cell development.

bioRxiv · Nov 27, 2025 · PreprintImmunology

Vascular and perivascular cell profiling reveals the molecular and cellular bases of blood-brain barrier heterogeneity

Sarah J. Pfau, Urs H. Langen, Theodore M. Fisher, Indumathi Prakash, Faheem Nagpurwala, Ricardo A. Lozoya, Wei-Chung Allen Lee, Zhuhao Wu, Chenghua Gu

The paper profiles vascular and perivascular cells in different brain regions to reveal molecular and cellular bases of blood-brain barrier heterogeneity.

bioRxiv · Apr 26, 2021 · PreprintNeuroscience